Vital nutrient for nerves, joints, tissue regeneration

SAM-e is S-Adenosylmethionine, a natural body chemical that is present in all living cells and is required in over 40 biochemical reactions. SAM-e is necessary for manufacturing certain neurotransmitters, hormones, proteins, the antioxidant glutathione and components of healthy joints. The body's level of SAM-e can be depleted by stress, aging or a diet low in proteins or methionine.

Users of SAM-e report a variety of health benefits. SAM-e may work more quickly for depression than St. John's wort. Benefits are often reported within days.

Each capsule contains 400 mg of S-adenosylmethionine tosylate, delivering 200 mg of SAM-e. Enterically coated caps for maximum absorption.

Research: SAM-e (135 clinical trials) appears to raise levels of dopamine, an important neurotransmitter in mood regulation, and higher SAMe levels in the brain are associated with successful drug treatment of depression.¹ Double-blind studies for depression² osteoarthritis³, fibromyalgia⁴, infertility ⁵, and migraine headaches⁶ have all shown benefits.  SAMe was also shown to replenish substances in damaged livers and improve the flow of bile.⁷

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(7) Lieber CS. Herman Award lecture, 1993: Am J Clin Nutr 1993;58:430–42